Substernal oxyphil parathyroid adenoma producing PTHrP with hypercalcemia and normal PTH level
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چکیده
منابع مشابه
Substernal oxyphil parathyroid adenoma producing PTHrP with hypercalcemia and normal PTH level
BACKGROUND Parathyroid adenoma is the most common cause of primary hyperparathyroidism. Preoperative serum calcium and intact-parathyroid hormone levels are the most useful diagnostic parameters that allow differentiating primary hyperparathyroidism from non-parathyroid-dependent hypercalcemia. Parathyroidectomy is the definitive treatment for primary hyperparathyroidism. Approximately 5% of pa...
متن کاملFunctioning oxyphil parathyroid adenoma.
A hormonally active oxyphil adenoma of the parathyroid masqueraded as a thyroid nodule and was present as a palpable neck mass for more than six years prior to the onset of clinically obvious hyperparathyroidism. The slow evolution of the hyperparathyroidism in the presence of a relatively large adenoma was correlated with the presumptive low hormonal synthetic capacity of oxyphil cells that fo...
متن کاملPTH-related peptide (PTHrP) in hypercalcemia.
It is now 20 years since the tumor-associated factor parathyroid hormone-related peptide was identified. Since then, there have been significant changes in the understanding of the hypercalcemic syndromes associated with malignancy and with the role of this peptide in normal physiology as well as this specialized pathologic setting. Parathyroid hormone-related peptide has become a useful diagno...
متن کاملThyroid follicular adenoma producing parathyroid hormone-related protein with a normal serum calcium level.
A 64-year-old woman had normal serum calcium and plasma parathyroid hormone levels, despite an extremely high plasma parathyroid hormone-related protein (PTHrP) level. She underwent medical screening at our hospital and several neck tumors were detected by ultrasonography. After surgical resection of these tumors, her plasma PTHrP level was normalized. Histological examination showed that the r...
متن کاملParathyroid carcinoma and oxyphil parathyroid adenoma: an uncommon case of misinterpretation in clinical practice.
A 46 year-old male presented with persistently high level of serum parathyroid hormone (PTH), despite successful resection of an oxyphilic cell parathyroid adenoma of the left lower gland. Renal function and serum calcium were normal, leading to vitamin D deficiency being considered. Tc99m-sestamibi parathyroid scintigraphy showed no capitation, but a cervical ultrasound demonstrated an increas...
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ژورنال
عنوان ژورنال: World Journal of Surgical Oncology
سال: 2008
ISSN: 1477-7819
DOI: 10.1186/1477-7819-6-24